Tag Archives: metaplastic breast cancer

Piece of Celery

Being of Finnish/Saami origin, I am a great coffee lover. When I first got home from the hospital after having breast cancer surgery my husband offered to make me a lovely latte. But strangely, what I wanted, craved for instead, was celery. This craving was much like those I had many years ago when I was pregnant. I needed it now! And I wanted it with V8 juice.
We had a bit of V8 juice left in the fridge. My darling Robert poured it into a glass and brought it to me, but it still needed more celery. He rummaged through the fridge and found a small, rather wilted piece of celery and added it to my glass of V8 juice. Nope, needed more celery. He found some celery salt in the spice drawer. I quickly glugged it all down. And still wanted more. Robert went to the corner shop and bought some more V8 and fresh celery. I drank several glasses before I felt satisfied.
Later I started to think about that, and wonder why celery? I got onto google and googled celery and cancer:
“Preventing cancer. Celery contains a flavanoid called luteolin. Researchers believe that luteolin may possess anti-cancer properties. A study published in Current Cancer Drug Targets said that “Recent epidemiological studies have attributed a cancer prevention property to luteolin.” Health benefits and risks of celery
Hmmm… Luteolin
So then I started to look for scientific research articles that have examined the effects of luteolin on cancer to see if there is any basis for this.

Triple Negative Breast Cancer
Although I wasn’t quite sure what type of breast cancer this was, the doctor thought it was probably Triple Negative Breast Cancer, based on the core biopsy that had been done the week before srugery. Triple Negative doesn’t have a good prognosis for recovery, because the cancer cells don’t have the hormone receptors that work with most of the current chemo treatments that are available.
These receptors are normally ER+ (estrogen)
PR+ (Progesterone)
HER2+ (Hormone epidermal growth factor receptor 2)
In my case, all these were Negative. ER-, PR- HER2-
Triple Negative Breast Cancer

So in my google research I decided to look for the effect of luteolin on Triple Negative Breast Cancer (TNBC). I did find a few encouraging articles, suggesting that I may be on the right track – perhaps foods can help to treat this almost incurable disease.
From what I can understand, it is thought that luteolin has some effect on preventing or slowing down the ability of cancer cells to spread to the lungs or other parts of the body.

Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells
“Most breast cancer-related deaths from triple-negative breast cancer (TNBC) occur following metastasis of cancer cells and development of tumors at secondary sites. Because TNBCs lack the three receptors targeted by current chemotherapeutic regimens, they are typically treated with extremely aggressive and highly toxic non-targeted treatment strategies. Women with TNBC frequently develop metastatic lesions originating from drug-resistant residual cells and have poor prognosis. For this reason, novel therapeutic strategies that are safer and more effective are sought. Luteolin (LU) is a naturally occurring, non-toxic plant compound that has proven effective against several types of cancer….Our findings show that LU effectively suppresses the viability of TNBC cells and blocks their metastasis to the lungs.”

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)
“Herein, we identified the off-patent compound luteolin, has the novel ability to block RSK/YB-1/Notch4 signaling and thereby inhibit TNBC growth including TIC-enriched populations. Since RSK has recently been identified as a TNBC-specific target, we focused on screening for compounds that have the ability to block RSK activity. We used a dual approach of high-throughput and virtual screening, as these are complementary methods that can be integrated to improve inhibitor discovery [51]. Notably, both screening techniques identified kaempferol, luteolin and apigenin that inhibited RSK1 and RSK2 at micromolar concentrations. Subsequent experiments identified luteolin as the lead compound as it suppressed growth in TNBC and inhibited RSK in cells. Consequently, it reduced phosphorylation of YB-1 and decreased Notch4 signaling, both of which are key pathways in sustaining TICs.
RSK2 is an emerging therapeutic target for developing treatments for TNBC, for which there are currently no targeted therapies available [11]. Our group identified that RSK2 specifically has the most potent inhibitory effect on growth in TNBC [10]. Furthermore, we propose that RSK inhibitors could have application beyond breast cancer to include other tumors that express high RSK2 such as those that develop in the lung, head and neck, prostate and hematopoietic system [52].”

I am a weaver. I am not an expert on any of this and don’t pretend to be. I was fortunate to be employed in an administrative role in the field of medical research for a few years, so developed a bit of skill in reading through research proposals so am familar with a few of the terms and what to look for in complex and technical scientific summaries and abstracts.
None of the information that I am writing about is to be construed as providing medical advice. Please contact your doctor and oncologist for advice regarding your condition.
Every cancer is different. I am merely documenting my own cancer journey as I try to figure out best decisions and solutions for myself.

If you would like to be notified of my next post please subscribe to All Fiber Arts Newsfeed or follow me on Twitter.

Celery and Cancer
Celery and Cancer

V8 Juice Recipe – My Fortified version
I purchased a juicer and I now make a V8 juice that has extra goodness added.
2-3 sticks of Celery
2-3 Carrots
2-3 Beets (cooked or raw)
Handful of Parsley leaves
Handful of Spinach
1/4 – 1/2 teaspoon Turmeric
1/4 – 1/2 teaspoon Cayenne Pepper
Mix this half and half with V8 Vegetable Juice.

Other Foods containing Luteolin
Celery
Parsley
Thyme
Broccoli

Below are links and books that have helped me with my cancer journey so far.

Links
Chris Beat Cancer

Recommended Books
Anticancer: A New Way of Life

The Cancer Survivor’s Guide: Foods That Help You Fight Back

Radical Remission: Surviving Cancer Against All Odds

How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease

Anticancer: A New Way of Life

Chris Beat Cancer: A Comprehensive Plan for Healing Naturally

[sc name=”Amazon-Bottom”]

Armus The Evil Villain

Every evil cancer must have a name. I called mine ‘Armus’

‘You say you are true evil. I say what true evil is – it is to submit to you. It is when we surrender our freedom, our dignity, instead of defying you.’

My battle with Armus, my breast cancer began on July 12, 2018.

Cancer never goes away. It is never cured. It is always with you, waiting to pop up again. So we must continue the battle and strengthen ourselves and our immune system to prevent its return.

Given the type of cancer that I had, I chose to have a mastectomy (just get this thing outa me!!) and to treat it holistically.

If you would like to be notified of my next post please subscribe to All Fiber Arts Newsfeed or follow me on Twitter.

Links
Chris Beat Cancer

Recommended Books
Anticancer: A New Way of Life

Radical Remission: Surviving Cancer Against All Odds

How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease

Anticancer: A New Way of Life

Chris Beat Cancer: A Comprehensive Plan for Healing Naturally

[sc name=”medianet300x250″]

[sc name=”Amazon-Bottom”]

My Life with Cancer

Charlie Brown and Snoopy
Charlie Brown and Snoopy

My Dear Fibre Friends,
It is difficult to write this but I feel that I must share my experiences as part of my healing process. In early July, I found a lump and went to visit my doctor. A mammogram, ultrasound and a core needle biopsy revealed that this was Stage 3 breast cancer. 6 Days later I found myself in hospital undergoing a radical mastectomy. 9 Lymph nodes were also removed during the procedure.
The lab results showed that this was not a standard type of breast cancer but an extremely rare form, called Metaplastic Breast Cancer. Depending on which study you read, only .02% – 1% of the population gets this type of cancer. The odd thing is that this cancer is not actually a breast cancer, but a type of Skin cancer that happened to grow within my breast. My doctor informed me that there are no known successful treatments for this type of cancer, therefore he does not recommend further chemo treatments. The chemo could possibly do more harm than good. I will also be meeting with my oncologist in a few weeks to discuss more details of this type of cancer and treatment options.
If there are no treatments that modern medicine can effectively provide, my best and only alternative is to look into holistic types of healing, using natural and organic foods, exercise, meditation and faith.
Due to the surgery, I have limited use of my right arm, so am unable to do any craft or textile work until my arm strengthens and heals.
I have had to cancel and postpone any workshops that I had scheduled. I closed my Etsy shop temporarily while I was going through surgery, but I have now reopened it. Products that I have made are available for sale. But I am unable to accept custom orders at this time until I regain the use of my hands. A portion of proceeds will be donated to Breast Cancer Research.
I will continue to post updates to my journey from time to time on my All Fiber Arts website.
If you would like to be notified of my next post please subscribe to All Fiber Arts Newsfeed or follow me on Twitter.

Paivi

[sc name=”Amazon-Bottom”]